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Louisville

2025 Season
Schedule Team Profile Recruiting Team Statistics Lineup

Season Schedule

Week 1
Spread Louisville -37.5
O/U 57.5
ML -7500/2000
Spread Louisville -38.0
O/U 56.5
Home: 21 | 20 | 7 | 3
Away: 0 | 7 | 0 | 10
Eastern Kentucky 0-0 (0-0)
@
Louisville 7-4 (0-0)
17 - 51
FINAL
Week 2
Spread Louisville -15.0
O/U 57
ML -700/475
Spread Louisville -15.5
O/U 56.5
ML -750/475
Home: 0 | 6 | 8 | 14
Away: 7 | 0 | 7 | 0
James Madison 8-1 (0-0)
@
Louisville 7-4 (0-0)
14 - 28
FINAL
Week 4
Spread Louisville -26.5
O/U 50.5
ML -4000/1600
Spread Louisville -26.5
O/U 51
ML -6500/1300
Spread Louisville -25.5
O/U 50.5
ML -5000/1500
Home: 7 | 14 | 9 | 10
Away: 3 | 0 | 0 | 14
Bowling Green 2-6 (0-0)
@
Louisville 7-4 (0-0)
17 - 40
FINAL
Week 5
Spread Louisville -3
O/U 53.5
ML 130/-155
Spread Louisville -3.0
O/U 54
ML 140/-165
Spread Louisville -3.5
O/U 52.5
ML 140/-165
Louisville 7-4 (0-0)
@
Pittsburgh 7-2 (0-0)
Sep 27, 2025 12:00 PM ET
Acrisure Stadium
Week 6
Spread Louisville -7
O/U 61.5
ML -250/205
Spread Louisville -7.0
O/U 62
ML -225/185
Spread Louisville -6.5
O/U 62.5
ML -240/200
Home: 7 | 7 | 0 | 10 | 3
Away: 7 | 7 | 10 | 0 | 6
Virginia 8-2 (0-0)
@
Louisville 7-4 (0-0)
30 - 27
FINAL
Week 8
Spread Miami -10.5
O/U 49.5
ML -440/340
Spread Miami -10.5
O/U 49.5
ML -425/320
Spread Miami -10.5
O/U 49.5
ML -550/390
Louisville 7-4 (0-0)
@
Miami 5-2 (0-0)
24 - 21
FINAL
Week 9
Spread Louisville -25.5
O/U 54.5
ML -2800/1300
Spread Louisville -25.5
O/U 54.5
ML -4000/1500
Spread Louisville -25.5
O/U 54.5
ML -2800/1100
Boston College 2-9 (0-0)
@
Louisville 7-4 (0-0)
24 - 38
FINAL
Week 10
Spread Louisville -10.5
O/U 53.5
ML 310/-395
Spread Louisville -10.5
O/U 53.5
ML 340/-450
Spread Louisville -10.5
O/U 53
ML 295/-390
Louisville 7-4 (0-0)
@
Virginia Tech 2-9 (0-0)
28 - 16
FINAL
Week 11
Spread Louisville -19.5
O/U 50.5
ML -1200/750
Spread Louisville -20.5
O/U 50.5
ML -1800/900
Spread Louisville -20.0
O/U 50.5
ML -1200/700
California 3-3 (0-0)
@
Louisville 7-4 (0-0)
29 - 26
FINAL
Week 12
Spread Louisville -1.5
O/U 50.5
ML -122/102
Spread Louisville -2.5
O/U 50.5
ML -125/105
Spread Louisville -1.5
O/U 51
ML -145/145
Clemson 7-5 (0-0)
@
Louisville 7-4 (0-0)
20 - 19
FINAL
Week 13
Spread SMU -3
O/U 52.5
ML -148/124
Spread SMU -3.5
O/U 53.5
ML -145/125
Spread SMU -3.0
O/U 52.5
ML -160/135
Louisville 7-4 (0-0)
@
SMU 4-2 (0-0)
6 - 38
FINAL
Week 14
Spread Louisville -3.0
O/U 46.5
ML -175/150
Spread Louisville -3
O/U 46.5
ML -148/124
Spread Louisville -3.5
O/U 47.5
ML -145/125
Kentucky 3-6 (0-0)
@
Louisville 7-4 (0-0)
0 - 41
FINAL